UKUSETYENZISWA OKUHLOSIWEYO
Inyathelo Eliqinileyo^®I-HPV 16/18 ye-Antigen Rapid Test Isixhobo luvavanyo olukhawulezayo olubonakalayo lovavanyo lomgangatho wokubhaqwa kwe-HPV 16/18 E6&E7 oncoproteins kwisampulu zeswabhu yomlomo wesibeleko yabasetyhini.Le kiti yenzelwe ukuba isetyenziswe njengoncedo ekuxilongeni umhlaza weCervical Pre-Cancer kunye noMhlaza.

INTSHAYELELO
Kumazwe asakhasayo, umhlaza womlomo wesibeleko ngoyena nobangela wokusweleka okunxulumene nomhlaza kwabasetyhini, ngenxa yokungaphunyezwa kovavanyo lokuhlola umhlaza womlomo wesibeleko waphambi komhlaza kunye nomhlaza.Uvavanyo lokuhlola useto lwezibonelelo eziphantsi kufuneka lube lula, lukhawuleze, kwaye lungabizi kakhulu.Ngokufanelekileyo, uvavanyo olunjalo luya kuba nolwazi malunga nomsebenzi we-HPV oncogenic.Ukubonakaliswa kwazo zombini i-HPV E6 kunye ne-E7 i-oncoprotein ibalulekile ukuze ukuguqulwa kweseli yomlomo wesibeleko kwenzeke.Ezinye iziphumo zophando zibonise ukuhambelana kwe-E6 & E7 kwi-oncoprotein positivity kunye nobunzima be-histopathology yomlomo wesibeleko kunye nomngcipheko wokuqhubela phambili.Ke, i-E6&E7 i-oncoprotein ithembisa ukuba yi-biomarker efanelekileyo ye-HPV-mediated oncogenic activity.

UMGAQO
Inyathelo Eliqinileyo^®I-HPV 16/18 i-Antigen Rapid Test Device yenzelwe ukufumanisa i-HPV 16/18 E6&E7 Oncoproteins ngokutolika okubonakalayo kophuhliso lombala kumgca wangaphakathi.I-membrane yayingashukumi kunye ne-monoclonal anti-HPV 16/18 E6&E7 antibodies kwindawo yovavanyo.Ngethuba lovavanyo, i-specimen ivumelekile ukuba iphendule nge-colored monoclonal anti-HPV 16/18 E6 & E7 antibodies enemibala edibeneyo ye-conjugates, eyayifakwe ngaphambili kwisampula yovavanyo.Emva koko umxube uhamba kwi-membrane ngesenzo se-capillary, kwaye udibanise nama-reagents kwi-membrane.Ukuba bekukho ngokwaneleyo i-HPV 16/18 E6 & E7 i-oncoproteins kwimizekelo, ibhendi enemibala iya kwenza kwindawo yovavanyo ye-membrane.Ubukho beli bhanti elinemibala libonisa umphumo omuhle, ngelixa ukungabikho kwawo kubonisa umphumo ombi.Ukubonakala kwebhanti enemibala kwindawo yokulawula isebenza njengolawulo lwenkqubo.Oku kubonisa ukuba umthamo ofanelekileyo we-specimen wongeziwe kwaye i-membrane wicking yenzeke.

UKUQOKELELWA KOMSEBENZI NOKUGCINWA
■ Umgangatho wesampulu efunyenweyo ubaluleke kakhulu.Nangona kuIseli ye-epithelial yomlomo wesibeleko kufuneka iqokelelwe nge-swab.Kwimizekelo yomlomo wesibeleko:
■ Sebenzisa kuphela i-Dacron okanye i-Rayon eneencam ezinencapha ezichuliweyo ezineeshafu zeplastiki.Yicebisa ukusebenzisa iswab enikezelwe ngumenzi wekhithi (Iswab ziayiqulathanga kule khithi, ngolwazi lokuodola, nceda uqhagamshelaneumenzi okanye umthengisi wendawo, inombolo yekhathalogu yi-207000).Iiswabskwabanye ababoneleli akukaqinisekiswa.Iiswabs ngeengcebiso zekotoni okanyeiishafu zomthi azikhuthazwa.
∎ Phambi kokuba kuqokelelwe isampulu, susa umfinya ogqithisileyo kwindawo ye-endocervicalnge-swab eyahlukileyo okanye ibhola yekotoni kwaye ulahle.Faka i swab kwiumlomo wesibeleko de kuvele imicu esezantsi kuphela.Jikelezisa ngokuqinileyo i-swabkuba 15-20 imizuzwana kwicala elinye.Tsala i-swab ngononophelo!
■ Musa ukubeka iswab kuso nasiphi na isixhobo sothutho esinesixhobo esiphakathi ukusukela okoisiphakathi sothutho siphazamisa uvavanyo kunye nokusebenza kwezinto eziphilayoayifuneki kuvavanyo.Beka i-swab kwi-tube yokukhutshwa, ukuba uvavanyoinokuqhutywa kwangoko.Ukuba uvavanyo olukhawulezileyo alunakwenzeka, isigulaneiisampulu kufuneka zifakwe kwityhubhu yokuthutha eyomileyo yokugcina okanye ukuthutha.Ii-swabs ingagcinwa iiyure ezingama-24 kwindawo yokushisa (15-30 ° C) okanye iveki enyekwi-4°C okanye hayi ngaphezulu kweenyanga ezi-6 kwi -20°C.Yonke imizekelo kufuneka ivunyelweukufikelela kwiqondo lokushisa kwe-15-30 ° C ngaphambi kokuvavanya.