UKUSETYENZISWA OKUHLOSIWEYO
TheStrongStep^®Uvavanyo lwe-SARS-CoV-2 IgM/IgG luvavanyo olukhawulezayo lwe-immuno-chromatographic ekubhaqweni ngaxeshanye kwe-IgM kunye ne-IgG antibodies kwi-SARS-CoV-2 intsholongwane egazini lomntu lonke, i-serum okanye iplasma.Uvavanyo lusetyenziswa njengoncedo ekufunyanisweni kwe-COVID-19.

INTSHAYELELO
ICoronavirus isasazwe ngokubanzi phakathi kwabantu, ezinye izilwanyana ezanyisayo kunye neentaka intsholongwane ye-RNA, ebangela ukuphefumla, izifo ze-enteric, i-hepatic kunye ne-neurologic.Iintlobo ezisixhenxe ze-coronavirus zaziwa ngokubangela izifo zabantu.Iintlobo ezine zentsholongwane - 229E, OC43, NL63 kunye ne-HKU1 - zixhaphakile kwaye zidla ngokubangela iimpawu zokubanda eziqhelekileyo kubantu abangakwazi ukuzikhusela.Ezinye iintlobo ezintathu-ezinzima kakhulu zokuphefumla isifo se-coronavirus (SARS-CoV), i-Middle East yokuphefumla isifo se-coronavirus (MERS-CoV) kunye neNoveli ye-Coronavirus ka-2019 (COVID-19) - zinemvelaphi yezoonotic kwaye ziye zanxulunyaniswa nesigulo esibulalayo ngamanye amaxesha, iCoronavirus. is zoonotic, nto leyo ethetha ukuba zinokudluliselwa phakathi kwezilwanyana kunye nabantu.Iimpawu eziqhelekileyo zosulelo ziquka iimpawu zokuphefumla, umkhuhlane, ukukhohlela, ukuphefumla nzima kunye nobunzima bokuphefumla.Kwiimeko ezimandundu, usulelo lunokubangela inyumoniya, isifo sokuphefumla esiqatha, ukusilela kwezintso kunye nokufa.Ii-antibodies ze-IgM kunye ne-IgG ukuya kwiNoveli yeCoronavirus ka-2019 inokufunyanwa kwiiveki ezi-1 ukuya kwezi-2 emva kokuvezwa.I-IgG ihlala ilungile, kodwa inqanaba le-antibody liyehla ixesha elongezelelweyo.

UMGAQO
TheStrongStep^®Uvavanyo lwe-SARS-CoV-2 IgM/IgG lusebenzisa umgaqo we-Immuno-chromatography.Isixhobo ngasinye sinemicu emibini, apho i-SARS-CoV-2 i-antigen ethile idityanisiwe ingashukumi kwi-nitrocellulose inwebu ngaphakathi kwefestile yovavanyo yesixhobo.I-IgM yempuku echasene nomntu kunye ne-anti-human IgG antibodies ezidityaniswe namaso elatex anemibala azishukumi kwi-conjugate pad yemicu emibini ngokulandelelanayo.Njengoko isampulu yovavanyo ihamba ngenwebu ngaphakathi kwesixhobo sovavanyo, imouse enemibala ye-IgM echasene nomntu kunye ne-anti-human IgG antibodies zenza i-latex conjugate complexes ezine-antibodies zabantu (IgM kunye/okanye i-IgG).Olu bunzima luqhubela phambili kwi-membrane ukuya kwindawo yovavanyo apho lubanjwe yi-SARS-CoV-2 ethile ye-antigen ephinda iphinde yakhiwe.Ukuba i-SARS-CoV-2 intsholongwane ye-IgG/IgM i-antibodies ikhona kwisampulu, nto leyo ekhokelela ekwenziweni kwebhendi enemibala kwaye ibonisa iziphumo zovavanyo ezilungileyo.Ukungabikho kweli bhanti enemibala ngaphakathi kwefestile yokuvavanya kubonisa umphumo wovavanyo olubi.Le ngqungquthela iqhubela phambili kwi-membrane ukuya kummandla wokulawula apho ibanjwe yibhokhwe ye-anti-mouse antibody kwaye yenza umgca wokulawula obomvu ongumgca wokulawula owakhelwe ngaphakathi oya kuhlala uvela kwifestile yovavanyo xa uvavanyo lwenziwa ngokufanelekileyo, kungakhathaliseki ubukho okanye ukungabikho kwezilwa-ntsholongwane ezilwa ne-SARS-CoV-2 kumzekelo.

AMANQAKU EKIT
1. Inyathelo elomeleleyo^®Ikhadi loVavanyo le-SARS-CoV-2 IgM/IgG kwisingxobo sefoil
2. Isampulu yesithinteli
3. Imiyalelo yokusetyenziswa

IZINTO EZIFUNEKAYO KODWA AKUNIKEZWE
1. Isingxobo sokuqokelelwa kweSepcimen
2. 1-20μL Pipetter
3. Isibali-xesha

Uvavanyo lulinganiselwe e-US ukuba lusasazwe kwiilabhoratri eziqinisekiswe yi-CLIA ukwenza uvavanyo olunzima kakhulu.

Olu vavanyo aluzange luhlolwe yi-FDA.

Iziphumo ezibi aziluthinteli usulelo oluqatha lwe-SARS-CoV-2.

Ukuba kukrokrelwa usulelo oluqatha, uvavanyo oluthe ngqo lwe-SARS-CoV-2 luyimfuneko.

Iziphumo zovavanyo lwe-antibody akufuneki zisetyenziselwe ukuxilonga okanye ukungabandakanyi usulelo oluqatha lwe-SARS-CoV-2.

Iziphumo ezincumisayo zisenokuba ngenxa yosulelo lwangaphambili okanye lwangoku lohlobo lwe-coronavirus engeyiyo i-SARS-CoV-2, efana ne-coronavirus HKU1, NL63, OC43, okanye 229E.