Yeyiphi indlela efanelekileyo?
-Ukuba isifo sosulelo lwe-SARS-cov-2
Ngeemeko eziqinisekisiweyo ze-covid-19, zaxela iimpawu zokuthengiswa kwezonyango zibandakanya umkhuhlane, ukukhohlela, iMyalgia okanye ukudinwa. Ukanti ezi mpawu azizizo iimpawu ezizodwa zeCovid-19 kuba ezi mpawu ziyafana nezona zifo zosulelekileyo zentsholongwane ezinje ngolusu. Okwangoku, intsholongwane ye-acid ye-Acid ye-PCR (RT-PCR), i-CT icinga kwaye ezinye iiparamitha ze-Hematology zezona zixhobo ziphambili zosulelo lwekliniki. Iikhitshi ezininzi zelebhu ziphuhlisiwe kwaye zisetyenziswa kwiimodeli zovavanyo zeCodd-19 nge-CDC yaseTshayina1, I-US CDC2kunye nezinye iinkampani zabucala. I-IGG / I-IGM Anti yovavanyo, indlela yovavanyo lwe-serologing, iyongezwa njengemilinganiselo yokuxilongwa kwi-China ihlaziyiweyo yeNovel Coronavirus (Covid-19), eyakhutshwa nge-3 kaMatshi1. Intsholongwane yentsholongwane i-nucleic acid ntr-prc isekhona yindlela yokuqonda isifo sokuqonda iCovid-19.
Amandla®I-Novel Coronavlrus (i-SARS-CoV-2) I-Interx ye-PRC ye-PCR ye-PCR ye-PCR
Ukanti ezi chithi zexesha lokwenyani ze-PCR, zikhangela izinto zofuzo zentsholongwane, umzekelo, kwimpumlo, ngomlomo, okanye iSwal Swabs, ihlupheke kwimida ye-Anal:
1) Ezi mvavanyo zinexesha elide eliguqukayo amaxesha kwaye zisebenza nzima; Ngokuqhelekileyo bathatha i-avareji ngaphezulu kwe-2 ukuya kwezi-3 ukwenza iziphumo.
2) Uvavanyo lwe-PCR lufuna iilebhu eziqinisekisiweyo, izixhobo ezibizayo kunye neengcali eziqeqeshiweyo ukuba zisebenze.
3) Kukho amanye amanani amabi obuxoki kwi-RT-PCR yeCovide-19. Inokubangelwa yi-SARS-2 yentsholongwane yentsholongwane kwi-Swab Swab Swimpary (i-novel coronavirus iyosulela iphecana eliphantsi, njenge-pulmonary allomori) kwaye uvavanyo alunakuchonga abantu abaye kulungelwa, kwaye icocekile intsholongwane eminqeni yabo.
Uphando nge-lirong zou et al4ifumanise ukuba imithwalo ephezulu yentsholongwane yafunyanwa kungekudala emva kokuba i-vistom ifumana, ngemilinganiselo ephezulu yentsholongwane efunyenwe empumlweni kunye ne-chicleic slid yokutsala i-sars-2 ifana nezabaguli4kwaye ibonakala yahlukile kuleyo ibonwa kwizigulana ezosulelwe yi-SARS-CoV-2.
Yang pan et al5Uhlolisiso lweesampulu ze-serial (i-sputum, umchamo, kunye nesitulo) kwiintsuku ezingama-5-6 emva kweesampulu zentsholongwane, i-Sputum isampulu ye-viaral ibonise imithwalo ephezulu yentsholongwane kune Iisampulu zeswayitha. Akukho ntsholongwane i-viral ifunyenwe kumchamo okanye iisampulu zesitulo kwezi zigulana zibini.
Uvavanyo lwe-PCR lunika isiphumo esihle xa intsholongwane isekhona. Iimvavanyo azinakubachonga abantu abaye kusebenza esichengeni, bahlaziya, kwaye bayicoca intsholongwane emizimbeni yabo. Ngokuphathelele, kuphela malunga ne-30% -50% yayiqinisekile ukuba i-PCR kwizigulana ezine-Novel coronavirus ye-coronavirus. Uninzi lweNovel Coronavirus Pneumonis izigulana azinakufunyaniswa ngenxa yovavanyo olubi lwe-acid, ukuze bangawafumani unyango oluhambelana ngexesha. Ukusuka kowokuqala ukuya kwi-Essing yesithandathu yeziKhokelo, sixhomekeke kwisiseko sokuqonda iziphumo zovavanyo lwe-nucleid, ezibangele impebha enkulu kwi-COSCINAID. Isibhedlele, sifile. Ngexesha lokuphila kwakhe, wayeneemvavanyo ezintathu ze-acid kwimeko yomkhuhlane kunye nokukhohlela, kwaye okokugqibela wafumana iziphumo ezilungileyo zePCR.
Emva kwengxoxo ngeengcali, kwagqitywa kwelokuba kwandise iindlela zokuvavanywa kwe-serum njengenqanaba elitsha loochwephesha. Ngelixa i-antid anti yovavanyo, ibizwa ngokuba ziimvavanyo zeSerological, ezinokuqinisekisa ukuba umntu wosulelwe nokuba amajoni abo omzimba uye wayicoca le ntsholongwane kaComid-19.
I-Sultstep® SARS-cov-2 Igg / IGM Anti yovavanyo olukhawulezayo
Uvavanyo lwe-Igg / i-Igm Antiuqu luya kunceda ekulandeleleni ngendlela esekwe kusulelo umntu oye wasulela, kuba iimeko ezininzi zibonakala zisasazeka kwizigulana ze-ASMMPMMOTIC ezingakwaziyo ukuchongwa ngokulula. Isibini esitshatileyo, umyeni waziva unethemba nge-PCR, umlinganiso we-PCR wakhe wayengenakuthi, kodwa iziphumo zovavanyo zibonisa ukuba wayene-antibodies, njengoko wenzayo umyeni wakhe.
I-assays ye-serological kufuneka iqinisekiswe ngononophelo ukuze uqiniseke ukuba basabela ngokuthembekileyo, kodwa kuphela kwii-antibodies ezichasene ne-inower yenoveli. Enye inkxalabo yayikukufana phakathi kweentsholongwane ezibangela i-syndrome enkulu yokuphefumla kunye neCovid-19 inokukhokelela ekusebenzeni kwakhona. I-Igg-i-Igm iphuhliswe nge-xue feng wang6ithathwa njengenokwazi ukusetyenziswa njengovavanyo lokhathalelo lwenqaku (i-PACT), njengoko inokwenziwa kufutshane nebhedi ngegazi lomnwe. I-Kit ineemvakalelo ezingama-88.66% kwaye zibuthile ezingama-90.63%. Nangona kunjalo, bekukho iziphumo ezibi nezibubuxoki.
Kwinguqulo ehlaziyiweyo ye-China yesifo sonyango kunye nesikhokelo sonyango kwisifo seNovel Coronavirus (Covid-19)1, amatyala aqinisekisiweyo achazwa njengamatyala atyholwa ahlangabezana nayo nayiphi na kwezi ndlela zilandelayo:
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UKUXHASA NOKUNIKELWA KWECOD-19
| Izikhokelo | Epapashiwe | Ikhrayitheriya eziqinisekisiweyo |
| Inguqulelo yesi-7 | I-3Mar.2020 | ❶ pcr ❷ nugs ❸ I-Igm + IGG |
| Inguqulelo yesi-6 | Ngo-18 kr.2020 | ❶ pcr ❷ nugs |
Ireferensi
I-1. Izikhokelo zokuchonga isifo kunye nonyango lwe-Novel Coronavirus Pneumonia (I-County yeSilingo se-7, IKomishini yezeMpilo yeSizwe yeRiphabliki yaseTshayina, ekhutshwe kwi-3.Mar.20)
http://www.nhc.gov.cn/yzygj/s7652m/203/A211114bD9AFD55b
2. Uphando lusebenzisa kuphela i-teral ye-RTR-PCR yokwazisa ngo-2019-NCOV
https: //www.cdc.gov/coronavirus/2019-9vv/lab
3. I-SINGAOPORE ibango lokusetyenziswa kuqala kuvavanyo lwe-anting custe ukulandelela usulelo lwe-coronavirus
https:
4.S-I-TIR-2 yentsholongwane kwi-vrals ephezulu yesakhiwo esiphezulu sezinto eziphefumlelweyo ngoFebruwari 19,2020.2020 DOI: 10.1056
5. I-SARS-2 kwi-TOV-2 kwiisampulu zeklinikhi isuse nge-20 kaFebruwari kaFebruwari ka-24, i-2020 (2016))
I-6. Ukuphucula ukusetyenziswa kweklinikhi ye-Igm ye-Igm edibeneyo ye-Anticture e-Anticture kwi-SARS-cov-2
I-Id ye-Issulelo i-Ing Orcid Id: 0000-0001-8854-275x
IXESHA LOKUQALA: UMar-17 ukuya ku-2020
